Selected Publications
2026
Dev S, Wang Y, Jung M, Ma Y, Mani S, Kabin E, Yuda R, Dong Y, Ralle M, Hamilton JP, Lutsenko S. ATP7B-maintained copper stores in myeloid progenitors are required for functional maturation of neutrophils. Cell Rep. 2026 Feb 24;45(2):116955. doi: 10.1016/j.celrep.2026.116955.
2025
Yuda RAA, Bea H, Kellett V, Kim J, Yang F, Choijilsuren HB, Park Y, Fu Y, Ha Z, Choi J, Luo LZ, Sun Z, Gao B, Jeong S, Resar LMS, Jung M*. Chronic alcohol consumption drives inflammaging and transposon derepression in hematopoietic stem and progenitor cells. bioRxiv. doi: https://doi.org/10.64898/2025.12.25.696246
Grandis JR, Li H, Harrison BH, Webster ALH, Pucilowska J, Nguyen A, Lee J, Mills GB, Gencel-Augusto J, Zeng Y, Long SR, Kim M, Lee RH, Kutler DI, Scognamiglio T, Brandwein-Weber M, Urken M, Khodos I, Stanchina E, Lin Y, Donovan FX, Chandrasekharappa SC, Jung M, Sanders MA, Smogorzewska A, Johnson DE. Patient-Derived Xenograft Models of Fanconi Anemia-Associated Head and Neck Cancer Identify Personalized Therapeutic Strategies. Journal of Clinical Investigation. 2025 Dec 16:e195334. doi: 10.1172/JCI195334.
Choi J, Jung M. Head and Neck Cancer in Fanconi Anemia: Clinical Challenges and Molecular Insights into a DNA Repair Disorder. Cancers (Basel). 2025 Sep 18;17(18). doi: 10.3390/cancers17183046. Review.
Jung M*#, Kim J#, Park Y, Ilyashov I, Yang F, Choijilsuren HB, Keahi D, Durmaz JA, Bea H, Goldfarb A, Stein MD, Wong C, White RR, Sridhar S, Noonan R, Wiley R, Carroll TS, Lach FP, Jeong S, Miranda I, Smogorzewska A*. ALDH9A1 Deficiency as a Source of Endogenous DNA Damage that Requires Repair by the Fanconi Anemia Pathway. Journal of Cell Biology. 2025 Jul 7;224(7): e202407141. doi: 10.1083/jcb.202407141
2024
Lee G, Wong C, Cho A, West JJ, Crawford AJ, Russo GC, Si BR, Kim J, Hoffner L, Jang C, Jung M, Leone RD, Konstantopoulos K, Ewald AJ, Wirtz D, Jeong S. E-Cadherin Induces Serine Synthesis to Support Progression and Metastasis of Breast Cancer. Cancer Res. 2024 Sep 4;84(17):2820-2835. doi: 10.1158/0008-5472.CAN-23-3082.
2022
Webster ALH, Sanders MA, Patel K, Dietrich R, Noonan RJ, Lach FP, White RR, Goldfarb A, Hadi K, Edwards MM, Donovan FX, Hoogenboezem RM, Jung M, Sridhar S, Wiley TF, Fedrigo O, Tian H, Rosiene J, Heineman T, Kennedy JA, Bean L, Rosti RO, Tryon R, Gonzalez AM, Rosenberg A, Luo JD, Carroll TS, Shroff S, Beaumont M, Velleuer E, Rastatter JC, Wells SI, Surrallés J, Bagby G, MacMillan ML, Wagner JE, Cancio M, Boulad F, Scognamiglio T, Vaughan R, Beaumont KG, Koren A, Imielinski M, Chandrasekharappa SC, Auerbach AD, Singh B, Kutler DI, Campbell PJ, Smogorzewska A. Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer. Nature. 2022 Dec;612(7940):495-502. doi: 10.1038/s41586-022-05253-4. Epub 2022 Nov 30.
Jung M. Inflammation fuels bone marrow exhaustion caused by Samd9l mutation. J Clin Invest. 2022 Nov 1;132(21). doi: 10.1172/JCI164136.
2021
Choijilsuren HB, Park Y, Jung M. Mechanisms of somatic transformation in inherited bone marrow failure syndromes. Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):390-398. doi: 10.1182/hematology.2021000271. Review.
Yang Z, Wu XS, Wei Y, Polyanskaya SA, Iyer SV, Jung M, Lach FP, Adelman ER, Klingbeil O, Milazzo JP, Kramer M, Demerdash OE, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Smogorzewska A, Vakoc CR. Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia. Cancer Discov. 2021 Sep;11(9):2300-2315. doi: 10.1158/2159-8290.CD-20-1542.
Jung M, Smogorzewska A. Endogenous formaldehyde destroys blood stem cells. Blood. 2021 Apr 15;137(15):1988-1990. doi: 10.1182/blood.2020010541.
Jung M, Mehta PA, Jiang CS, Rosti RO, Usleaman G, Correa da Rosa JM, Lach FP, Goodridge E, Auerbach AD, Davies SM, Smogorzewska A, Boulad F. Comparison of the clinical phenotype and haematological course of siblings with Fanconi anaemia. Br J Haematol. 2021 Jun;193(5):971-975. doi: 10.1111/bjh.17061.
2020
Jung M, Ramanagoudr-Bhojappa R, van Twest S, Rosti RO, Murphy V, Tan W, Donovan FX, Lach FP, Kimble DC, Jiang CS, Vaughan R, Mehta PA, Pierri F, Dufour C, Auerbach AD, Deans AJ, Smogorzewska A, Chandrasekharappa SC. Association of clinical severity with FANCB variant type in Fanconi anemia. Blood. 2020 Apr 30;135(18):1588-1602. doi: 10.1182/blood.2019003249.
2018
Jung M, Cordes S, Zou J, Yu SJ, Guitart X, Hong SG, Dang V, Kang E, Donaires FS, Hassan SA, Albitar M, Hsu AP, Holland SM, Hickstein DD, Townsley D, Dunbar CE, Winkler T. GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells. Blood Adv. 2018 Dec 11;2(23):3553-3565. doi: 10.1182/bloodadvances.2018017137.
Asur RS, Kimble DC, Lach FP, Jung M, Donovan FX, Kamat A, Noonan RJ, Thomas JW, Park M, Chines P, Vlachos A, Auerbach AD, Smogorzewska A, Chandrasekharappa SC. Somatic mosaicism of an intragenic FANCB duplication in both fibroblast and peripheral blood cells observed in a Fanconi anemia patient leads to milder phenotype. Mol Genet Genomic Med. 2018 Jan;6(1):77-91. doi: 10.1002/mgg3.350.
2017
Schlums H, Jung M, Han H, Theorell J, Bigley V, Chiang SC, Allan DS, Davidson-Moncada JK, Dickinson RE, Holmes TD, Hsu AP, Townsley D, Winkler T, Wang W, Aukrust P, Nordøy I, Calvo KR, Holland SM, Collin M, Dunbar CE, Bryceson YT. Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells. Blood. 2017 Apr 6;129(14):1927-1939. doi: 10.1182/blood-2016-08-734236.
Hong SG, Yada RC, Choi K, Carpentier A, Liang TJ, Merling RK, Sweeney CL, Malech HL, Jung M, Corat MAF, AlJanahi AA, Lin Y, Liu H, Tunc I, Wang X, Palisoc M, Pittaluga S, Boehm M, Winkler T, Zou J, Dunbar CE. Rhesus iPSC Safe Harbor Gene-Editing Platform for Stable Expression of Transgenes in Differentiated Cells of All Germ Layers. Mol Ther. 2017 Jan 4;25(1):44-53. doi: 10.1016/j.ymthe.2016.10.007.